Carelon Research perspectives

Insights intended to advance evidence-based healthcare

Designing real-world

White paper: Designing real-world evidence studies for causal inference

 

May 2023

 

In this white paper, experts from Carelon Research seek to increase understanding of the factors that inform the design and conduct of causal studies in real-world settings.

 

Read article

formerly HealthCore

A conversation with the co-founders of Carelon Research (formerly HealthCore, Inc.): Mark Cziraky and Marcus Wilson

 

January 2022

 

The co-founders of Carelon Research (formerly HealthCore, Inc.) reflect on the journey from 1996 and the recent brand transition to Carelon Research.

 

Read article

Innovative approaches

Carelon Research impact study: Innovative approaches to gathering the patient perspective

 

July 2022

 

The patient-centered research team at Carelon Research goes beyond numbers to inform meaningful research solutions with rich, in-depth insights.

 

Read article

Clinical oncology research solutions

Clinical oncology research solutions

 

July 2022
 

The data environment, relationships, and research expertise at Carelon Research position us to deliver high-quality, actionable results, saving you time and effort.

 

Read article

Causal inference for real-world evidence

Causal inference for real-world evidence

 

July 2022

 

Carelon Research offers highly specialized scientists, access to a robust source of integrated real-world data, and decades of experience necessary for successfully employing these methods.

 

Read article

Our next chapter

A letter from the president: Our next chapter

 

July 2022

 

HealthCore (now Carelon Research) is joining the Carelon family of companies under Elevance Health.

 

Read article

vaccine safety

Carelon Research impact study: Using background incidence rates to inform vaccine safety

 

July 2022

 

This study provides context for potential safety events that may arise among children and adults vaccinated with a pneumococcal vaccine.

 

Read article

clinical oncology data

Carelon Research impact study: Validation of integrated claims and clinical oncology data

 

July 2022

 

Researchers at Carelon Research examined the validity of the CCQP data relative to information abstracted from the redacted medical records of breast, lung, and colorectal cancer patients.

 

Read article

causal inference

What is causal inference and when do you need it?

 

July 2022

 

Causal inference is used to answer cause and effect research questions and yield estimates of effect (as opposed to associations).

 

Read article

Marfan Syndrome

Carelon Research impact study: Atenolol versus Losartan in children and young adults with Marfan Syndrome

 

April 2022

 

The Marfan study is one of several landmark studies to which Carelon Research has contributed statistical and regulatory oversight, and data and project management.

 

Read article

Research impact study

Carelon Research impact study: A Sentinel data partner and scientific collaborator

 

March 2022

 

From the time that the FDA began the Sentinel Initiative, Carelon Research has been a key data partner and collaborating institution.

 

Read article

Elements of a good survey

Survey research: Elements of a “good” survey

 

January 2022

 

After determining that a survey is the best method for obtaining answers to their research questions, researchers should consider the elements of a “good” survey.

 

Read article

birth prediction

Carelon Research impact study: Cost effectiveness of a proteomic test for preterm birth prediction

 

November 2021

 

This study is one of the first economic evaluations using real-world data to assess the potential value of the PreTRM test for preterm birth risk in a commercially insured U.S. population.

 

Read article

real-world evidence

What is real-world evidence and why is it important?

 

November 2021

 

Real-world data and real-world evidence are more than just buzzwords. They’re becoming increasingly important for informing healthcare decisions across a number of settings and stakeholders.

 

Read article

Topiramate in pregnancy

Carelon Research impact study: Topiramate use in pregnancy and the birth prevalence of oral clefts

 

August 2021

 

A collaborative study by Carelon Research and our partners found that first trimester exposure to topiramate is associated with an increased prevalence of oral clefts.

 

Read article

25th anniversary

Carelon Research celebrates 25th anniversary of Founder’s Day: A letter from the president

 

July 2021

 

Twenty-five years have passed since we set out on this journey. Our mission to advance the derivation and utilization of real-world evidence continues.

 

Read article

drug safety and effectiveness

Real-world evidence complements randomized clinical trials to enhance drug safety and effectiveness

 

February 2021

 

Carelon Research conducted one of the first real-world studies investigating the safety of palbociclib, the most widely prescribed CDK4/6 inhibitor in the treatment of HR+/HER2- advanced stage breast cancer.

 

Read article

Predictive modeling

Predictive modeling and machine learning: Sharpening the focus of real-world evidence in the age of precision medicine

 

April 2020

 

The use of statistical methods to develop better case-identifying algorithms enables use of claims databases to study rare diseases and other targeted indications.

 

Read article

machine learning

The power of machine learning

 

October 2019

 

Machine learning combines advanced statistical methods with the results from validation studies to construct new case-identifying algorithms.

 

Read article

pediatric research

A leader in pediatric research for 30 years

 

October 2019

 

Since its founding, Carelon Research’s clinical research team has been deeply involved in conducting, and collaborating on, research with children and infants.

 

Read article

pragmatic trials

The value of pragmatic trials to regulators

 

October 2019

 

Regulatory agencies have expressed interest in using pragmatic trial-generated evidence in regulatory decision-making.

 

Read article

life science product developers

The value of pragmatic trials to life science product developers

 

October 2019

 

For the biopharmaceuticals industry, pragmatic trials uniquely offer solutions to address the growing demands of healthcare payers and policy makers.

 

Read article

clinicians

The value of pragmatic trials to clinicians

 

October 2019

 

For clinicians, pragmatic trials generate evidence that enables better-informed decision making.

 

Read article

HEOR trends

HEOR trends: Going broad and deep in real-world evidence

 

October 2019

 

Carelon Research has the data assets and expertise necessary for going broad and deep in real-world evidence generation.

 

Read article

growing war against opioids

The growing war against opioids

 

October 2019

 

As activities and significant events related to opioids, including abuse and misuse play out, safety and epidemiology research is providing insights into the effectiveness of these efforts.

 

Read article

Ready to learn more? Let's connect.